Searchable abstracts of presentations at key conferences in endocrinology

ea0099oc6.3 | Oral Communications 6: Environmental Endocrinology | ECE2024

NRF2 genetic polymorphisms modify the longitudinal association of serum polychlorinated biphenyls with glucose homeostasis damage: A gene-environment interaction analysis among Chinese general adults

Tan Qiyou , Zhou Min , Yu Linling , Wang Bin , Wang Mengyi , Chen Weihong

Background: As persistant organic pollutants, polychlorinated biphenyls (PCBs) are widespread in environment worldwide. Serum PCBs and nuclear factor erythroid 2-related factor 2 (NRF2) are associated with glucose homeostasis damage in the general population. However, there is a lack of epidemiological evidence on the interaction between serum PCBs and NRF2 gene in relation to glucose homeostasis damage.Objectives: We aimed to explore the intera...

ea0099oc6.5 | Oral Communications 6: Environmental Endocrinology | ECE2024

Assessing the interaction of styrene/ethylbenzene exposure with genetic susceptibility in type 2 diabetes mellitus: insights from a cohort study

Yu Linling , Tan Qiyou , Zhang Yongfang , Wang Bin , Chen Weihong

Background: Styrene and ethylbenzene (S/EB), the monomers found in polystyrene (PS) and polyethylene (PE), are known to continuously leach into the environment and food products. The prevalent use of hand sanitizers containing S/EB during the COVID-19 pandemic has heightened concerns about the health implications of S/EB exposure. Notably, the impact of S/EB exposure on the risk of type 2 diabetes mellitus (T2DM) and its interaction with genetic factors in the general populati...